Introducing Yerba Maté Tea to Your Colon

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Friday, 10 February 2012 20:21

Urbana, Illinois, February 2012— Could preventing colon cancer be as simple as developing a taste for yerba maté tea? In a recent University of Illinois study, scientists showed that human colon cancer cells die when exposed to the approximate number of bioactive compounds present in one cup of this brew, which has long been consumed in South America for its medicinal properties.   “The caffeine derivatives in mate tea not only induced death in human colon cancer cells, they also reduced important markers of inflammation,” said Elvira de Mejia, a U of I associate professor of food chemistry and food toxicology.   That’s important because inflammation can trigger the steps of cancer progression, she said.   In the in vitro study, de Mejia and former graduate student Sirima Puangpraphant isolated, purified, and then treated human colon cancer cells with caffeoylquinic acid (CQA) derivatives from mate tea. As the scientists increased the CQA concentration, cancer cells died as a result of apoptosis.   “Put simply, the cancer cell self-destructs because its DNA has been damaged,” she said.   The ability to induce apoptosis, or cell death, is a promising tactic for therapeutic interventions in all types of cancer, she said.   The results of the study strongly suggest that the caffeine derivatives in maté tea have potential as anti-cancer agents and could also be helpful in other diseases associated with inflammation, she said.   “If we can reduce the activity of the important marker that links inflammation and cancer, we’ll be better able to control the transformation of normal cells to cancer cells,” she added. This in vitro study was published in Molecular Nutrition & Food Research, vol. 55, pp. 1509-1522, in 2011. Co-authors include Sirima Puangpraphant, now an assistant professor at Kasetsart University in Thailand; Greg Potts, an undergraduate student at the U of I; and Mark A. Berhow and Karl Vermillion of the USDA, ARS, National Center for Agricultural Utilization Research in Peoria, Illinois. The work was funded by the U of I Research Board and Puangpraphant’s Royal Thai Government Scholarship.   SOURCE: University of Illinois (Visual courtesy hookedoniron.com) < Prev   Next >